Grapes are widely recognized as a popular fruit crop that has witnessed significant growth in production and the introduction of new varieties over the past twenty years. Therefore, improving vegetative growth and chemical content are important. This study was conducted in a private vineyard located west of Bani Mazar Center; Minia Governorate was chosen for this investigation. Trials were carried out in 2019 and 2020 over the course of two seasons on 16-year-old Roomy Red grapevine cultivars grown on their own roots. To study the effect of two commercial products, namely; Stimulant and Acadian, with different levels (0, 0.25, 0.5, and 1 g/L) for each one in a randomized complete block design, on the vegetative growth aspects and leaves chemical content of Roomy Red grapevines. The result of the present work suggests that spraying Acadian was the best choice on Roomy Red grapevines at 1 g/L, followed by 0.5 g/L without statistical difference, and recorded the uttermost mean values of studied vegetative growth aspects and chemical content during both seasons of the experiments. It can be recommended that foliar application with 0.5 g/L recorded the best economical results.