The jackfruit tree is a rare tropical fruit in Egypt. Although seedlings are created through seed propagation, they grow slowly, especially in the nursery stage. During the period from 2022-2023 to 2023-2024 seasons, research was conducted at the Aswan Botanical Garden in Egypt to examine the effects of gibberellins (GA₃) and combination sodium nitrophenolate (CSN) on the chemical compositions and growth rate of jackfruit (Artocarpus heterophylls L.) seedlings. Three replications of the randomized complete block design (RCBD) were used in the experiment. Nine treatments were applied including combinations of CSN and GA₃ with three concentrations (0, 100, and 200 ppm). The results proved that treating seedlings with different treatments improved growth and chemical compositions compared to the control. Among nine treatments spraying seedlings with CSN (200 ppm) + GA₃ (100 ppm), followed by CSN (100 ppm) + GA₃ (200 ppm) gave superior performance in plant height, leaves number/plant, stem diameter, fresh and dry weight of the plant, number of roots, leaf area, and the amount of total chlorophyll, total carbohydrates, flavonoids, N, P, and K in the leaves. The findings indicated that CSN has a good impact on some mechanisms that regulate the growth and development of plants. Additionally, GA₃ promotes apical dominance, enhances growth, and plays a useful part in the physiological functions of the plant.