This present study focused on the response of Al-Saidy date palm fruit quality under New Valley governorate – Egypt in relation to replacement of the traditional NPK mineral fertilizers by using nano NPK fertilizers, individually or in combination. Field experiment included fourteen treatments from traditional and nano fertilizers were achieved on fifty-six female palms of Al-Saidy date palm cv. grown in sandy soil, during 2018 and 2019 seasons. The present investigation shows that using the nano NPK fertilizers shows superior to using the traditional NPK fertilizers. However, all nano NPK combinations present significant effect than using each element individually. The best fruit physical and chemical parameters were obtained whine the palms received the three elements in combination in form of nano fertilizers. These results were true during both seasons.