A field experiment was carried out during two successive seasons (2019 and 2020) in new reclamation land under Minia Governorate conditions. The obtained data showed that spraying Wonderful pomegranate trees at any concentration used 250, 500, 750 ppm for mega flower, 100 ppm amino acids and 100 ppm for salicylic acid significantly enhanced all vegetative growth parameters (i.e. shoot lengths, number of leaves/shoot, number of new shoots/ tree and leaf area), leaves main pigments (chlorophylls and carotenoids), yield (kg/ tree), fruit number/tree and average fruit weight. The data showed that, all combined treatments between the three examined compounds (mega flower, amino acids and SA) was more effective than any of them alone. The trees received mega flower at 750 ppm combined with amino acids and SA each at 100ppm present the best results.