Flame Seedless cultivar is one of the most popular grape cultivar in Egypt. However, in Minia region, it faces some problems such as poor yield and poor coloration of berries, which in turn negatively affect marketing of such grapevine cv. The present study was conducted during two seasons 2017 and 2018 on Flame
seedless grapevines in order to study the possibility of using single and combined inoculation with Arbuscular Mmycorrhizal fungi (AMF), Azospirillum brasilense bacteria (AZSB) and Azotobacter chrococcum bacteria
(AZBB) on improving productivity and fruit quality of Flame Seedless grapevines grown clay soil under Minia region conditions, Egypt. The obtained results confirmed that inoculation the vines with the three examined
microorganisms (AMF, AZSB and AZBB) individually or in combination was remarkably improved the yield and its components, berries physical properties and berries chemical properties comparison to un-inoculated vines.
Furthermore, any combined inoculation was more effectiveness on yield and berries physical and chemical than the individual inoculation, during the two experimental seasons. The vines inoculated with the mixture of the three
microorganism's AFM+AZSB+AZBB in-combination gave the highest yield and best berries physical and
chemical properties.