Under salt and drought stress conditions, sweet potato plants are producing secondary metabolites.
Redox active secondary metabolites occasionally produced to accommodate changes arising in their fluctuating
growth conditions, which in role enable functional flexibility. In the current study, transcriptome sequencing was
applied for understanding the redox active secondary metabolites related genes and its pathway under stress
conditions as compared to control plants. The obtained transcripts were annotated using BlastX search against
NR_NCBI database to identify the sequence similarity with the available online sequence data. The detected upregulated genes were involved in metabolic pathways as well as abiotic stress resistance. These up-regulated
transcripts were aligned to 10 different known genes including 4-coumarate--CoA ligase-like 10 (4 CL)，9-cisepoxycarotenoid dioxygenase chlorophyll(ide) b reductase NYC1 (chloroplastic)，cytochrome P450 82C2-like
，cytochrome P450 82C4-like, cytochrome P450 CYP72A219-like，cytochrome P450 CYP82D47-like isoform
X1，Homogentisate 1,2-dioxygenase，methyltransferase DDB_G0268948 and Phosphoethanolamine Nmethyltransferase 1-like. Detected down-regulated individual genes in the current experiment were involved in
processes related to plant metabolic pathways. Some of these genes were significantly expressed in high levels at
the beginning of stress then started to decrease with increasing the stress duration. This indicated that they are
early responsive genes to stress, which contribute in determining plant resistance and growth at the second phase
of stress. The down-regulated individual genes were aligned to 9 different known genes namely 24-
methylenesterol C-methyltransferase 2, 3-oxoacyl-[acyl-carrier-protein] synthase I, cytochrome P450 71A3-like,
cytochrome P450 76A1-like isoform X2, cytochrome P450 76A2-like, cytochrome P450 76C2-like, geraniol 10-
hydroxylase-like protein, geraniol 8-hydroxylase-like and tocopherol O-methyltransferase, chloroplastic isoform
X1. This study of hexaploid sweet potato redox active secondary metabolites related genes are providing valuable
source for breeding applications. Additionally, it offers new candidate genes to breed salt and drought tolerant
sweet potato cultivars.